It is possible to change a rendition by overriding it. The following 0300-biggerThumbnails.json file changes the size of the doclib image from 100x100 to be 123x123 and introduces another rendition called biggerThumbnail that is 200x200.
{ "renditions": [ { "renditionName": "doclib", "targetMediaType": "image/png", "options": [ {"name": "resizeWidth", "value": 123}, {"name": "resizeHeight", "value": 123}, {"name": "allowEnlargement", "value": false}, {"name": "maintainAspectRatio", "value": true}, {"name": "autoOrient", "value": true}, {"name": "thumbnail", "value": true} ] }, { "renditionName": "biggerThumbnail", "targetMediaType": "image/png", "options": [ {"name": "resizeWidth", "value": 200}, {"name": "resizeHeight", "value": 200}, {"name": "allowEnlargement", "value": false}, {"name": "maintainAspectRatio", "value": true}, {"name": "autoOrient", "value": true}, {"name": "thumbnail", "value": true} ] } ] }