In order to check in and out documents from OnBase, you must have EDM Briefcase installed on your system.
If you are using the EDM Briefcase in a virtual environment, the OnBase Client may be using a different version of the EDM Briefcase than the version used by the standalone EDM Briefcase. In this case, the two versions are compatible, but the earlier version will not reflect the later version's enhancements. You can check the version by selecting Help | About EDM Briefcase in the EDM Briefcase.
To avoid erratic behavior, do not use separate versions of the EDM Briefcase on the same workstation.