BizTalk Server Requirements - Enterprise Integration Server - English - Foundation 22.1 - OnBase - Premier - external - Standard - Premier - Standard - OnBase/Enterprise-Integration-Server/English/Foundation-22.1/Enterprise-Integration-Server/Enterprise-Integration-Server-Configuration/Consuming-the-Hyland-Adapter-with-BizTalk-Server/BizTalk-Server-Requirements - 2022-08-18

Microsoft BizTalk Server 2010, 2013, 2013 R2, and 2016 are the only versions of BizTalk Server supported by the Enterprise Integration Server module. Microsoft BizTalk Server 2010, 2013, or 2016 is included with the Enterprise Integration Server module. The version of Microsoft BizTalk Server that is included with the Enterprise Integration Server module can only be used in conjunction with OnBase.