After you have created and configured send and receive handlers, you must update the BizTalk application's send ports and receive locations with these newly created send and receive handlers.
- In the BizTalk application, select Send Ports.
- Right-click a send port and select Properties.
- In the Send Port Properties dialog box, select the newly created send handler from the Send handler drop-down list.
- Click OK.
- Repeat the above steps for the BizTalk application's Receive Locations.
- Start all host instances, applications, receive locations, and send ports.